The “Up In Smoke” Tour — billed as “a historical summit of the reigning leaders of hip-hop” — will feature the five multi-platinum artists and surprise guests.

Twenty-five tour stops, mostly indoor arenas, have been confirmed so far and organizers said they expect the show to touch down in approximately 40 cities. The first few dates are set to go on sale this weekend.

The five headliners, most of whom have known each other for more than 10 years, said they envision the show to be a “family affair that celebrates the diversity and mass appeal of their audience, bringing together fans of all cultures, races, ages and status.”